Abstract:There is a great deal of interest in the use of cannabis-based products including medically authorized marijuana for the treatment of almost any pain condition including low back pain. There are many anecdotal reports of patients who found it an effective treatment for chronic low back pain, one that has allowed them in some cases to discontinue other treatments such as continuing opioid therapy. There is now easy legal access to cannabis-based preparations in Canada with or without medical authorization. However, with some notable exceptions, the evidence that would allow physicians to have a high degree of confidence in selecting this treatment modality is lacking.
Key Words: cannabis; chronic pain; low back pain; evidence.
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1. Compared to medically authorized cannabis, street sourced products are at high risk of contamination including insect remains, fungi, chemical fertilizers and herbicides.
2. Unlike most plant-sourced medications, the active ingredients are located on the cannabis leaf, which raises the risk of contaminant exposure.
3. Cannabis leaves by themselves are inert until heated in a process known as decarboxylation.
4. While inhaled cannabis has a rapid onset of action, ingested products have a delayed onset producing a risk of overdose if continuing to consume while waiting for an expected effect.
5. Little is yet known about potential drug interactions with cannabis use.
Cannabis authorizing physicians will often recommend a higher THC:CBD ratio product for evening or bedtime use, and a higher CBD:THC ratio or pure CBD for daytime use.
As is true for any potential intoxicant, patients need to be cautioned about the risks of operating a motor vehicle or any machinery while under the influence of cannabinoids, especially higher THC ratio products.
Because it is a lipid soluble chemical, urine, blood, or hair tests can detect THC for many days after use.
Standardized tools and principles exist for the appraisal of credible eHealth resources.
Physicians in Canada provide medical "authorization" for cannabis use, verifying that the patient has a medical condition for which cannabis could be a valid therapeutic option. This authorization then allows the patient to purchase from a licensed producer up to a recommended quantity in grams per day. Although the basic patient demographics and birthday are required, unlike a prescription, the exact component percentage and potency, method of ingestion, and frequency are not components of the authorization.
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1 is an associate professor in the Division of Orthopaedic Surgery at the University of Ottawa and is cross- appointed to the School of Epidemiology and Public Health. He is head of the University's Adult Spinal Surgery Program and is the medical lead for the region's ISAEC program. His research interests involve regional and systems-based strategies to improve physical activity in back pain. 2is an associate professor at the Telfer School of Management. His doctoral studies centered on the impact of information and communication technologies on activities such as telemedicine and e-learning. His current research program is developing methodologies that enhance healthcare practitioners care delivery. 3 is a PhD candidate at the Telfer School of Management. His research focuses on the use of behaviour change theories to anchor the design of digital technologies. Specifically, he is interested in designing systems to facilitate habit formation for users.4 completed his Masters in Epidemiology from the University of Toronto's Faculty of Medicine. He is currently the Director of Research Operations for the Canadian Spine Outcomes and Research Network.5is a Professor in the Department of Surgery at the University of Toronto. He is the Medical Director, CBI Health Group and Executive Director of the Canadian Spine Society in Toronto, Ontario.
Abstract:Electronic Health (eHealth) technologies for back pain care, including websites and mobile apps, are rapidly growing. Unfortunately, the clear majority are unregulated and not considered credible. Given this growth, clinicians require the tools to help their patients navigate through the "wild west" of options towards more trustworthy platforms. Artificial Intelligence and digital technologies anchored in behaviour change theories have the potential to further transform these eHealth platforms.
Key Words: Electronic Health (eHealth) technologies, back pain care, websites, mobile apps, artificial intelligence.
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The Canadian Agency for Drugs and Technologies in Health (CADTH) has published a summary for users entitled "Can you trust Dr. Google," and it recommends that users look at the Author, Date (current), Objectivity, Purpose, Transparency and Usability.
Clinicians should become familiar with several credible eHealth resources to recommend to patients when assisting with their self-management of back pain.
Electronic Health platforms have the potential to engage patients in the self-management of their back pain.
Most available eHealth options for back pain are considered unreliable and not credible; however, several government and professional societies are beginning to publish reliable and useful content for patients.
Standardized tools and principles exist for the appraisal of credible eHealth resources.
Artificial Intelligence and anchoring mobile health solutions in behaviour change theories may further improve eHealth platforms.
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1 Faculty of Medicine, University of British Columbia, Vancouver, BC. 2Clinical Associate Professor, Department of Pediatrics, Associate Member, Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, BC.
Abstract: Atopic dermatitis is a common pediatric disease with a chronic relapsing-remitting course, causing distress to patients and family. In patients who remain recalcitrant following treatment with topical steroids, adjunctive therapies including bleach baths, wet wraps and phototherapy as well as systemic immunosuppressants may be considered. Many novel therapies are in development and act on various aspects of the immunologic cascades involved in atopic dermatitis. The following review briefly summarizes up-to-date evidence for the use of these therapies in the pediatric population.
Topical corticosteroids, the first-line treatment for atopic dermatitis, can be optimized with usage of an appropriate amount and within a supportive, therapeutic alliance.
Those who fail to improve with topical corticosteroids may benefit from adjunctive treatment with wet wraps, bleach baths and phototherapy with narrowband UV therapy. These have been shown to be efficacious with a minimal side effect profile.
In those who remain recalcitrant, a brief course of immunosuppressants may be indicated. Methotrexate, azathioprine and cyclosporine have evidence in the pediatric population. Of these, methotrexate has been shown to have the most sustained duration of remission.
A recent explosion of novel immunomodulators and biologics may redefine atopic dermatitis treatment. Crisaborole is a topical PDE4 inhibitor, which has been approved for used in children. Dupilumab is an injectable monoclonal antibody, which has recently been approved for the adult population and remains off-label in pediatrics.
Monotherapy when possible and regular check-ins with parents can improve adherence to topical steroid regimens, particularly within the first 3 days of treatment.
The American Academy of Dermatology recommends the use of bleach baths (1/2 cup of 6% household bleach in a 150L bathtub full of water) for 5 to 10-minute intervals 2-3 times weekly as an adjunct to topicals.
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Dementia can be terrifying and devastating to both caregivers as well as the loved ones affected by this disease. People with this disease can now feel some relief due to technological advancement which is meant to improve the quality of their lives. This technology can enhance autonomy as well as independence, manage possible risks in homes and get rid of stress.
In this article, we are going to look at the 5 technological innovations for those with Dementia
1. Communication Aids
Interacting with others is necessary for the quality of life in memory care. Individuals with dementia can remember how an event has made them feel, even if they are unable to recall the faces and names. Technology has simplified the interaction process with loved ones. Adapted telephones are now programmed with contacts that are frequently dialed and usually have bigger buttons which simplify their usage. It's now possible to stay connected with loved ones who are distant apart via the video chat services.
"Changes in the brain caused by dementia begin years before diagnosis. And throughout this timeframe, there are no clear signs that that person has dementia." comments Jane Byrne, Project Coordinator at FirstCare.1
2. Electrical appliance use monitoring
This innovation is meant for caregivers who do not stay together with their loved ones. It controls the use of electrical apparatuses through plugging into a power strip or wall outlet as it will notify caregivers when their appliances have been switched on or off. These technologies do not make the diagnosis of dementia easy. This disease is yet overwhelming. The dementia is now more manageable; this is due to the innovation in new technologies.
3. Reminder messages
Reminders play an important role as the caregiver does as they help to keep the loved ones safe and also retain their relationships. The recording of these messages is done on a device in the residential area and then played out loud at the most suitable time. Caregivers can record a message that when played reminds an individual to take medication at the appropriate time. Some gadgets are designed to play messages based on individuals activity. Some devices are meant to remind individuals with dementia to lock the front door when leaving home. There are other reminder messages designed to help people with dementia on when to close the door when to go to bed and provide reassurance at times when the caregiver is not present.
4. Home care robots
Technological advancement has led to the invention of homecare robots which will help reduce the caregiver duty. They are not designed to replace human caregivers, but instead, they are meant to do overall housework and remind individuals who are suffering from dementia on when to take medication or notify medical experts when assistance is required. With further inventions, home care robots may replace caregivers and handle their responsibility fully.
5. In-home cameras
In-home cameras are another technological innovation that is meant to enhance the safety of your loved ones from a distance.2 By either positioning, the camera focusing on medication or in the entrance room can increase your confidence as you are sure your loved one is taking the necessary medication and also active. These cameras can monitor movements and also enable one to communicate with his or her loved one. It will also notify you if no movements have been detected for a particular period.
References
1Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario. 2Clinical Associate Professor, Department of Pediatrics, Associate Member, Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, BC.
Abstract: Superficial fungal infections are a common occurrence in adults and children alike. Dermatophytes are the primary cause of these infections, which generally present as erythematous, scaling, annular lesions. Also referred to as "tinea", these infections are classified based on where they are found on the body, as different locations can have slightly different presentations and treatment requirements. This article provides an overview of these various presentations of dermatophyte infections and their risk factors, as well as recommended therapies.
Dermatophyte infections, also known as tinea, are very common fungal infections in humans. They occur on the superficial skin, hair, and nails, and can present in many different locations on the body.
Tinea captis is most common in children and can cause hair loss or abscess formation.
When tinea infections are treated with topical corticosteroids, they become harder to detect and are referred to as tinea incognito.
Tinea infections are common, but should be confirmed with KOH microscopy and/or culture from a skin scraping, nail clipping,
or hair sample.
Tinea capitis can be mistaken for eczema or seborrheic dermatitis
Check patients who have tinea infection for tinea pedis, since this is a common source of infection for sites on the rest of the body
Treatment for dermatophyte infections can include oral antifungal agents such as terbinafine or grise-ofulvin in a weightdependent
dose, or topical antifungal agents. Systemic agents are generally re-served for presentations that penetrate hair follicles and nails, or those that are refractory to topical treatment.
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Abstract: Calcified nodules are uncommon in the base of tongue. Solitary amyloid metaplasia can occur at the base of the tongue and can produce calcification and are difficult to diagnose by histopathological examination.1 Ossoeus choristoma of the tongue is a rare benign condition producing calcified nodule in the base of the tongue.2 Unusual ectopic osseous tongue masses are reported in dermoid cysts or teratomas.3 Osteoma of the base is also reported in the literature.4 Venous malformations with phleboliths are also described in the literature5 causing calcified nodules at the base of tongue.
There are various conditions like ectopic thyroid, lipoma, lymphoma, lymphoid hyperplasia and metastatic lymphatic spread can present with base of tonge swelling. Only a few conditions discussed in the article can have calcified nodule at the base of the tongue.
Base of tongue pathology can be easily missed unless prompt examination, investigations and management is done.
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