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Acne Vulgaris: 2023 Update

Teaser: 

Amir Gohari1 Joseph M. Lam, MD, FRCPC,2

1 University of British Columbia, Vancouver, British Columbia, Canada.
2Department of Pediatrics, Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

CLINICAL TOOLS

Abstract: Acne vulgaris is a chronic pilosebaceous inflammatory disorder that affects almost 85% of those aged 12 to 24 years. Its pathophysiology is an interplay between androgenic activity, follicular epidermal hyperproliferation, retention hyperkeratosis, and Cutibacterium acnes infection. Strong evidence exists for high glycemic index diet as a trigger. Diagnosis is clinical and management is based on lesion types, with options including retinoids, benzoyl peroxide, antibiotics, oral contraceptives, and spironolactone.
Key Words: acne vulgaris, inflammatory disorder, comedones, Cutibacterium acnes.
Acne vulgaris is the most common skin condition observed in adolescent and pre-adolescent patients and has a significant psychological burden.
The plugged follicles of acne allow for Cutibacterium acnes overgrowth which triggers the release of heat shock proteins, porphyrin, proteases, and squalene peroxides, leading to inflammation.
Topical retinoids are used for open and closed comedones, while topical antibiotics and benzoyl peroxide are used for inflammatory lesions. Oral antibiotics are added for moderate to severe inflammatory acne. Hormonal therapy and isotretinoin are used to target the excess sebum production.
Acne may reflect an underlying disease. Patients that present before 7 years of age may have an underlying endocrinopathy. For women with acne, the possibility of polycystic ovary syndrome (PCOS) should be addressed.
Acne lesions can be non-inflammatory, in the form of open or closed comedones, and/or inflammatory, in the form of papules, pustules, and nodules. Treatment should be targeted to the type of acne the patient presents with.
To have access to full article that these tools were developed for, please subscribe. The cost to subscribe is $80 USD per year and you will gain full access to all the premium content on www.healthplexus.net, an educational portal, that hosts 1000s of clinical reviews, case studies, educational visual aids and more as well as within the mobile app.
Related Terms: Dermatology, acne vulgaris, inflammatory disorder, comedones, Cutibacterium acnes
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#23: Rosacea

Welcome to 3P: Pills, Pearls, and Patients where we will discuss current events in medicine, stories from real patient-physician encounters, and gain insight into what it's like being a physician in today's society.

Please note that while the first episode is available to listen to without registration, accessing additional episodes will require you to subscribe and log in.

  Back to Pills, Pearls & Patients (3P)

 

Hello and welcome to the next episode of 3P, Pills, Pearls and Patients. Today, we're going to continue our series in dermatology. And we're speaking about rosacea.
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Dr. Marina Malak is a family physician in Mississauga, Ontario and a lecturer and faculty member at the University of Toronto. She is actively involved in medical advocacy, and is a board member of the Mississauga Primary Care Network. She is also a member of the National Committee of Continuing Professional Development at the College of Family Physicians of Ontario, and a member of the Research Ethics Board at Trillium Health Partners.

She is passionate about patient care; medical education; and promoting mental, physical, and emotional wellness. She enjoys reading, writing, public speaking, puzzles, doodling in her bullet journal, and creating drawings on Procreate.

Degenerative Cervical Myelopathy: Navigating Management in the Primary Care Setting

Teaser: 

Karlo M. Pedro, MD,1 James Milligan, MD,2 Michael G. Fehlings, MD, PhD,3

1 Division of Neurosurgery, Krembil Neuroscience Centre, University Health Network, Toronto, ON, Canada.
2 McMaster University, Department of Family Medicine, Hamilton, ON, Canada.
3Division of Neurosurgery and Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada.

CLINICAL TOOLS

Abstract: Degenerative cervical myelopathy (DCM) is a progressive and acquired spinal disorder that represents a potentially reversible cause of spinal cord impairment among adults. It remains underdiagnosed due to a low level of awareness amongst the public and healthcare professionals. Diagnosis is anchored on high clinical suspicion after a thorough history and physical examination and confirmed using magnetic resonance (MR) imaging of the cervical spine. Improving early diagnosis and ensuring timely surgical intervention are crucial in preventing long-term disability and optimizing long-term outcomes for DCM patients.
Key Words:degenerative cervical myelopathy, myelopathy, non-traumatic spinal cord injury, primary care.

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Pre-test CME Quiz Post-test CME Quiz
DCM is the most common cause of non-traumatic spinal cord dysfunction among adults worldwide
DCM is a potentially reversible disease with profound neurologic implications if left untreated
A thorough history and physical examination, supplemented with MR imaging of the cervical spine, are key elements to avoid misdiagnosis and delays in management
The hallmark signs of DCM are deterioration of hand motor function (eg. decreased coordination/clumsiness) as well as gait instability
MRI is the imaging of choice to confirm a diagnosis of DCM
Surgery is the only proven therapy that can halt the progression of DCM
To have access to full article that these tools were developed for, please subscribe. The cost to subscribe is $80 USD per year and you will gain full access to all the premium content on www.healthplexus.net, an educational portal, that hosts 1000s of clinical reviews, case studies, educational visual aids and more as well as within the mobile app.
Related Terms: Back Health, degenerative cervical myelopathy, myelopathy, non-traumatic spinal cord injury, primary care

Bubby Sized up the World

Teaser: 

I'm not the only one that had a grandmother (bubby in Yiddish) who profoundly affected my life.

Related Terms: Medical Narratives
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#22: Atopic Dermatitis

Welcome to 3P: Pills, Pearls, and Patients where we will discuss current events in medicine, stories from real patient-physician encounters, and gain insight into what it's like being a physician in today's society.

Please note that while the first episode is available to listen to without registration, accessing additional episodes will require you to subscribe and log in.

  Back to Pills, Pearls & Patients (3P)

 

Hello and welcome to the next episode of 3P, Pills, Pearls and Patients. Today, we're continuing our series on dermatology. And today we're talking about Atopic Dermatitis, also known as eczema.
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Dr. Marina Malak is a family physician in Mississauga, Ontario and a lecturer and faculty member at the University of Toronto. She is actively involved in medical advocacy, and is a board member of the Mississauga Primary Care Network. She is also a member of the National Committee of Continuing Professional Development at the College of Family Physicians of Ontario, and a member of the Research Ethics Board at Trillium Health Partners.

She is passionate about patient care; medical education; and promoting mental, physical, and emotional wellness. She enjoys reading, writing, public speaking, puzzles, doodling in her bullet journal, and creating drawings on Procreate.

#20: Introduction to Dermatology

Welcome to 3P: Pills, Pearls, and Patients where we will discuss current events in medicine, stories from real patient-physician encounters, and gain insight into what it's like being a physician in today's society.

Please note that while the first episode is available to listen to without registration, accessing additional episodes will require you to subscribe and log in.

  Back to Pills, Pearls & Patients (3P)

 

Hello and welcome to the next episode of 3P, Pills, Pearls and Patients. I'm your host, Dr. Marina Malak. And today we're going to kick off a three series, a three part series episode on Dermatology. So today's going to be the Introduction to Dermatology. And then we're going to have two episodes, one on atopic dermatitis and one on acne.
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Dr. Marina Malak is a family physician in Mississauga, Ontario and a lecturer and faculty member at the University of Toronto. She is actively involved in medical advocacy, and is a board member of the Mississauga Primary Care Network. She is also a member of the National Committee of Continuing Professional Development at the College of Family Physicians of Ontario, and a member of the Research Ethics Board at Trillium Health Partners.

She is passionate about patient care; medical education; and promoting mental, physical, and emotional wellness. She enjoys reading, writing, public speaking, puzzles, doodling in her bullet journal, and creating drawings on Procreate.

#19: Chronic Constipation

Welcome to 3P: Pills, Pearls, and Patients where we will discuss current events in medicine, stories from real patient-physician encounters, and gain insight into what it's like being a physician in today's society.

Please note that while the first episode is available to listen to without registration, accessing additional episodes will require you to subscribe and log in.

  Back to Pills, Pearls & Patients (3P)

 

Hello and welcome to the next episode of 3P, Pills, Pearls and Patients. I'm your host, Dr. Marina Malak. And today we have the interesting conversation going about chronic constipation. As is usual, I'm going to preface that I am no way an expert. I do not claim to be a GI specialist or an expert in treating constipation or pelvic physiotherapy or any of the things we're going to talk about here.But definitely seen my fair share of constipation among patients. And I'm sure you guys have as family health care providers have seen it as well.
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Dr. Marina Malak is a family physician in Mississauga, Ontario and a lecturer and faculty member at the University of Toronto. She is actively involved in medical advocacy, and is a board member of the Mississauga Primary Care Network. She is also a member of the National Committee of Continuing Professional Development at the College of Family Physicians of Ontario, and a member of the Research Ethics Board at Trillium Health Partners.

She is passionate about patient care; medical education; and promoting mental, physical, and emotional wellness. She enjoys reading, writing, public speaking, puzzles, doodling in her bullet journal, and creating drawings on Procreate.

#18: Introduction to Urogenital Health

Welcome to 3P: Pills, Pearls, and Patients where we will discuss current events in medicine, stories from real patient-physician encounters, and gain insight into what it's like being a physician in today's society.

Please note that while the first episode is available to listen to without registration, accessing additional episodes will require you to subscribe and log in.

  Back to Pills, Pearls & Patients (3P)

 

Hello and welcome to the next episode of 3P, Pills, Pearls and Patients. I'm your host, Dr. Marina Malak. And today we're going to kick off a two part series on Urogenital Health. Today's episode is going to be more of an introduction, and the next episode is going to talk about constipation. So stick around for some good information about a system that's often neglected. And I think for many reasons.
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Dr. Marina Malak is a family physician in Mississauga, Ontario and a lecturer and faculty member at the University of Toronto. She is actively involved in medical advocacy, and is a board member of the Mississauga Primary Care Network. She is also a member of the National Committee of Continuing Professional Development at the College of Family Physicians of Ontario, and a member of the Research Ethics Board at Trillium Health Partners.

She is passionate about patient care; medical education; and promoting mental, physical, and emotional wellness. She enjoys reading, writing, public speaking, puzzles, doodling in her bullet journal, and creating drawings on Procreate.