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peri-operative pain management

Opioid Use in Patients Undergoing Spine Surgery

Teaser: 

Eric J. Crawford MD, FRCSC,1 Ronit Kulkarni,2 Rajesh Kumar MBBS, FRCS, FCPS, FACS, FEBNS, MRCPS,3 Ted Findlay DO, CCFP, FCFP,4 Christopher J. Nielsen MD, FRCSC,5 Stephen J. Lewis MD, FRCSC,6 Robert A. Ravinsky MDCM, MPH, FRCSC,7

1 Divisions of Orthopaedic and Spine Surgery, Sunnybrook Health Sciences Centre, Toronto, ON.
2 Medical University of South Carolina, College of Medicine, Charleston, SC.
3Division of Spine Surgery, Sunnybrook Health Sciences Centre & Department of Surgery, University of Toronto, Toronto, ON.
4Calgary Chronic Pain Center at Alberta Health Services, Calgary, AB.
5Division of Orthopaedic Surgery, Toronto Western Hospital, University Health Network & Department of Surgery, University of Toronto, Toronto, ON.
6Division of Orthopaedic Surgery, Toronto Western Hospital, University Health Network & Department of Surgery, University of Toronto, Toronto, ON.
7Department of Orthopaedics and Physical Medicine, Medical University of South Carolina, Charleston, SC.

CLINICAL TOOLS

Abstract: Opioid medications have long been known for their analgesic properties and play an important role in the treatment of acute post-surgical pain. However, in recent years there has been an increase in chronic opioid therapy (COT) for painful conditions, in particular spinal disorders. These patients can have increased postoperative analgesic requirements and may be at increased risk of complications after surgery. In this evidence-based review, we provide guidance for managing opioid and analgesic medications for patients on COT from the preoperative assessment to post-surgical management including recommendations for appropriate opioid reduction.
Key Words: low back pain, surgery, opioid sparing, peri-operative pain management.

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1. Pre-operative chronic opioid usage is associated with poorer surgical outcomes.
2. Pre-operative chronic opioid usage is associated with prolonged post-surgical opioid therapy.
3. Pre-operative opioid tapering can achieve clinical surgical outcomes comparable to an opioid-naïve group.
4. Non-pharmacological or non-narcotic medications may help reduce pre-operative opioid usage.
5. A clear plan for a post-surgical opioid taper should be prepared prior to surgery.
The OPAL trial notes that opioids for acute non-specific low back or neck pain present no significant difference to placebo for pain at 6 weeks.
Buprenorphine is commonly used as an opioid rotation pre-operatively to assist in opioid weaning.
Discontinuing opioid prescriptions should be considered if there is a lack of overall and clinically meaningful improvement in function, quality of life or pain, or lack of progress towards meeting agreed therapeutic goals.
Gabapentin in doses over 1800 mg/day is associated with 60% increased odds of opioid related death.
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