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clinical outcome

Diagnosis and Management of Heart Failure with Preserved Ejection Fraction in Older Adults

Diagnosis and Management of Heart Failure with Preserved Ejection Fraction in Older Adults

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George A. Heckman, MD, MSc, FRCPC, Assistant Professor of Medicine, Department of Medicine, McMaster University, Hamilton, ON.
Robert S. McKelvie, MD, PhD, FRCPC, Professor of Medicine, Department of Medicine, McMaster University Hamilton, ON.

Heart failure (HF) is usually associated with reduced left ventricular ejection fraction, but approximately 50% of all patients with HF have a preserved ejection fraction. The mortality and morbidity associated with this condition, which may be the most common form of HF in older persons, is substantial and is on the rise. Currently, there are few evidence-based therapies demonstrated to be beneficial for this condition. The usual therapeutic recommendations consist of the aggressive management of the comorbidities and fluid balance associated with this form of HF. Disease management programs may improve outcomes among older persons with HF and preserved ejection fraction.
Key words: heart failure, diastolic dysfunction, preserved ejection fraction, treatment, clinical outcome.